Discover the 5 essential steps of Vitamin D synthesis, from UVB activation to kidney conversion, and learn about related disorders like rickets, CKD, and osteoporosis.
Author: amit2k8pmch
Pathophysiology of Different Types of Rickets.
Explore the pathophysiology of different types of rickets, including nutritional, genetic, and renal causes. Understand key mechanisms behind calcium and phosphate metabolism disorders.
Clinical Signs and Symptoms of Refeeding Syndrome
Refeeding syndrome is a life-threatening condition in malnourished patients receiving rapid nutrition. Learn about its clinical signs, symptoms, and step-by-step management, including electrolyte correction and prevention strategies.
Human Milk Banking
Human milk banking plays a crucial role in providing safe donor breast milk to vulnerable neonates. This article covers the definition, importance, donor criteria, collection, storage, nutritional composition, physiology of lactation, and indications for human milk banking
Human Milk: Composition, Bioactive Properties, and Benefits
Discover the unique composition and bioactive factors of human milk. Learn how it differs from cow’s milk, its immunological benefits, and why it prevents hypoglycemia and anemia in infants. Understand breastfeeding advantages, lactation physiology, and common breastfeeding problems with management tips.
Obstructive Sleep Apnea (OSA) in Children
Obstructive Sleep Apnea (OSA) in children is a serious sleep disorder caused by airway obstruction, leading to snoring, restless sleep, and daytime fatigue. This article covers its pathophysiology, clinical features, diagnosis (including polysomnography), and management strategies, including surgical and non-surgical options.
Diagnostic Algorithm for a Child with Failure to Thrive (FTT)
Failure to thrive (FTT) is a condition where a child’s growth falls significantly below expected norms. It can be caused by medical (organic) or psychosocial (non-organic) factors. This article outlines a step-by-step diagnostic approach, red flags, and management strategies for both types of FTT.
Approach to a 6-Year-Old Boy with Short Stature
A stepwise approach to evaluating a 6-year-old boy with short stature, including history, physical examination, differential diagnosis, key investigations, and management strategies. Learn how to differentiate normal variants from pathological causes
A 12-year-old female child with short stature and delayed puberty
A 12-year-old girl presenting with short stature and delayed puberty requires a thorough evaluation to determine the underlying cause. Common etiologies include normal variants (constitutional growth delay, familial short stature), endocrine disorders (growth hormone deficiency, hypothyroidism, Turner syndrome), chronic illnesses (celiac disease, CKD, IBD), and genetic syndromes. A stepwise diagnostic approach includes bone age assessment, hormonal tests, and karyotyping when needed. Early identification and targeted management—such as growth hormone therapy, thyroid hormone replacement, or nutritional interventions—can significantly improve outcomes.
Severe Combined Immunodeficiency (SCID) Presenting as Persistent Fever with Persistent Leukocytosis and Lymphopenia in a 10-Month-Old Female: A Case Report
AbstractSevere Combined Immunodeficiency (SCID) is a rare, life-threatening primary immunodeficiency disorder characterized by defective T- and … Severe Combined Immunodeficiency (SCID) Presenting as Persistent Fever with Persistent Leukocytosis and Lymphopenia in a 10-Month-Old Female: A Case ReportRead more