A 12-year-old female child with short stature and delayed puberty
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A 12-year-old female child with short stature and delayed puberty

A 12-year-old girl presenting with short stature and delayed puberty requires a thorough evaluation to determine the underlying cause. Common etiologies include normal variants (constitutional growth delay, familial short stature), endocrine disorders (growth hormone deficiency, hypothyroidism, Turner syndrome), chronic illnesses (celiac disease, CKD, IBD), and genetic syndromes. A stepwise diagnostic approach includes bone age assessment, hormonal tests, and karyotyping when needed. Early identification and targeted management—such as growth hormone therapy, thyroid hormone replacement, or nutritional interventions—can significantly improve outcomes.

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Severe Combined Immunodeficiency (SCID) Presenting as Persistent Fever with Persistent Leukocytosis and Lymphopenia in a 10-Month-Old Female: A Case Report

AbstractSevere Combined Immunodeficiency (SCID) is a rare, life-threatening primary immunodeficiency disorder characterized by defective T- and … Severe Combined Immunodeficiency (SCID) Presenting as Persistent Fever with Persistent Leukocytosis and Lymphopenia in a 10-Month-Old Female: A Case ReportRead more