Treatment of urticaria and angioedema Antihistamines H1 second generation Dose 6 m- <2 year 2.5 ml BD (15mg BD) >2-11 year 5ml BD(30 mg BD) >12 year 60 mg BD Adult 180 mg once daily Tab allegra 30 ,60,180 Levocetrizine Dose 6 months -5 years:1.25 mg once daily 6- 11 year […]
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ATAXIA TELANGIECTASIA Ataxia telangiectasia is a complex syndrome with immunologic, neurologic, endocrinologic, hepatic, and cutaneous abnormalities. Clinical Manifestations The most prominent clinical features are progressive cerebellar ataxia, oculocutaneous telangiectasias, chronic sinopulmonary disease , a high incidence of malignancy, and variable humoral and cellular immunodeficiency. Recurrent sinopulmonary infections occur in approximately 80% of these patients. Although
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Understanding Rett Syndrome: The Rat GAMES Mnemonic Rett Syndrome is a rare neurological disorder that predominantly affects girls and leads to severe cognitive and physical impairments. To help medical professionals and students remember the key features of Rett Syndrome, the mnemonic **”Rat GAMES”** is often used. Rat GAMES Mnemonic: – Rat: Regression of development usually
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Bardet Biedl Syndrome (BBS), also known as Laurence Moon Biedl Syndrome It is a rare genetic disorder with a variety of clinical features and complications. This syndrome is characterized by a constellation of symptoms affecting multiple body systems. Clinical Features of Bardet-Biedl Syndrome (Laurence Moon Biedl Syndrome) 1. Obesity: One of the hallmark features of
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Dyskeratosis Congenita Telomerase DISorder Mnemonics- TELOMERx Disorder T – Teeth abnormal and carious E -Epiphora ( due to nasolacrimal duct obstruction ) L- Leucoplakia in oral cavity ( tongue and buccal mucosa)O M – Marrow failure ( severe aplastic anemia) MDS E – Excessive sweating from palm and sole Rx – Androgen HSCT D-
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Understanding Growing Pains in Children Growing pains are a common experience for many children aged 3 to 12 years old. These pains, often described as non-articular and intermittent bilateral aches, typically occur in the legs during the evening or at night. Understanding the nature of growing pains and how to manage them can help alleviate
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Understanding Sydenham Chorea (St. Vitus Dance) Sydenham chorea, also known as St. Vitus dance, is the most common acquired chorea of childhood, occurring in 10-20% of children who have had acute rheumatic fever. This condition usually manifests weeks to months after an infection with group A β-hemolytic streptococci, with a peak incidence at ages 8-9
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CHRONIC GRANULOMATOUS DISEASE Mnemonics: CHRONIC Granulomatous Disease C -Catalase positive organism( staphylococcus aureus , Serrantia marcescens) recurrent infection . H- HSCT is only known cure R- Resemble like Chrons disease O- Osteomyelitis, pneumonia , LN and skin Infections are most common illnesses encountered N-NBT test now rarely used. NADPH oxidase component defects I -Itraconazole prophylaxis
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CLASSICAL HOMOCYSTINURIA key points of classical homocystinuria H- High dose of Vitamin B6 is required for treatment+ folic acid sometimes O – Ocular (ectopia lentis) M- Marfan like features ( Arachnodactyly, scoliosis, high arched palate, crowding of teeth , pes cavus ,genu valgum O – Osteoporosis of spine is common Cy- Cysthionine $ synthase (CBS)
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Understanding Congenital Toxoplasmosis and the Mnemonic “3C” Introduction Congenital toxoplasmosis is a serious parasitic infection caused by Toxoplasma gondii. This infection can be transmitted from a pregnant mother to her fetus, potentially leading to severe complications. The risk of transmission is highest during the third trimester, although the earlier the infection in pregnancy, the more
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