Best mnemonics for chronic Granulomatous Disease 2024

CHRONIC GRANULOMATOUS DISEASE


Mnemonics: CHRONIC Granulomatous Disease

C -Catalase positive organism( staphylococcus aureus ,     Serrantia marcescens) recurrent infection .

H- HSCT is only known cure

R- Resemble like Chrons disease

O- Osteomyelitis, pneumonia , LN and skin Infections are most common illnesses encountered

N-NBT test now rarely used.
      NADPH oxidase component defects

I -Itraconazole prophylaxis reduces the frequency of fungal infection.

C – Cytometry(flow) using DHR helps in diagnosis.
        Corticosteroids useful for treatment of children with antral and urethral obstruction or severe granulomatous colitis .

Granuloma : Granuloma are hallmarks .They cause pyloric outlet obstruction, bladder outlet or ureter obstruction.

Disease: Defective generation of microbicidal oxygen metabolites.
               D is 4th letter 4 genes ( 1 XLR 3AR)

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