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- Hematuria:
- Glomerular: Post-streptococcal glomerulonephritis, IgA nephropathy
- Non-glomerular: Stones, infections, trauma, tumors
- Hemoglobinuria:
- Hemolysis (e.g., G6PD deficiency, sickle cell disease)
- Severe infections (malaria, sepsis)
- Myoglobinuria:
- Rhabdomyolysis (trauma, vigorous exercise)
- Drugs:
- Rifampin, phenazopyridine, laxatives (senna), beets (food pigments)
- Metabolic Disorders:
- Others:
- Dehydration (concentrated urine mimicking red)
- Menstrual contamination
Approach for Evaluation of a Child with Headache
- History:
- Onset and pattern: Acute vs. chronic, episodic vs. progressive
- Location: Frontal, occipital, bilateral
- Quality: Throbbing, pressure-like, stabbing
- Duration: Minutes to days
- Associated symptoms: Nausea, vomiting, photophobia, fever, seizures
- Triggers: Stress, sleep deprivation, certain foods, exertion
- Red flags: Early morning headaches, neurological deficits, personality changes
- Examination:
- Vitals: Blood pressure, pulse
- Neurological exam: Cranial nerves, motor, sensory, reflexes, gait
- Fundoscopy: Check for papilledema
- Head and neck: Sinus tenderness, neck stiffness
- Investigations:
- Basic labs: CBC, ESR/CRP (inflammatory markers)
- Neuroimaging: MRI/CT if red flags are present
- Lumbar puncture: If meningitis or increased intracranial pressure suspected
- Common Diagnoses:
- Migraine: Pulsating, photophobia, nausea, aura
- Tension headache: Bilateral, dull, tight sensation
- Secondary causes: Meningitis, hydrocephalus, intracranial mass, hypertension
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